The Nanomedicine Lab has a mission to generate and disseminate fundamental knowledge in the field of nanomedicine at the convergence of nanotechnology, bioengineering, pharmacology and neurotechnology.
Clinical translation of advanced materials as integral components of next generation therapeutics, diagnostics and medical devices by safe and socially responsible pathways is our ultimate goal.
LAB PUBLICATIONSVIEW ALL
bioRxiv, 2025, in press
Graphene micro-transistor arrays reveal perfusion-dependent electrophysiological and haemodynamic signatures of cortical spreading depolarizations in ischaemic stroke
S. Flaherty, A. Eladly, K. Hills, J. Merlini, E. Masvidal-Codina, E. Fernandez, X. Illa, E. Prats-Alfonso, E. Del Corro, J.A. Garrido, J. Meents, K. Kostarelos, S Allan, A. Guimerà-Brunet*, R.C. Wykes*
FULL ABSTRACT
Nature Reviews Clinical Oncology, 2025, 22
Targeting the glioblastoma resection margin with locoregional nanotechnologies
Thomas Kisby, Gerben R. Borst, David J. Coope, Kostas Kostarelos*
FULL ABSTRACT
Journal of Nanobiotechnology 23, 393 (2025)
Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells
Yingxian Chen, Vinicio Rosano, Neus Lozano, YuYoung Shin, Aleksandr Mironov, David Spiller, Cinzia Casiraghi, Kostas Kostarelos*, Sandra Vranic*
FULL ABSTRACT
bioRxiv, 2025, in press
An artefact-resilient wide bandwidth bidirectional graphene neural interface
Michał Prokop, Martín Esparza-Iaizzo, Eduard Masvidal-Codina, Xavi Illa, Neela K. Codadu, Daman Rathore, Nicola Ria, Kostas Kostarelos, Elena del Corro, Ramon Garcia-Cortadella, Rob C. Wykes, Anton Guimerà-Brunet*, Jose A. Garrido*
FULL ABSTRACT
bioRxiv, 2025, in press
Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing post-operative spatiotemporal blood-brain barrier disruption
Lorena F. Fernandes, Chariya Peeyatu, Ben R. Dickie, Yu Siong Ho, Lydia A. Thompson, Noelia Hernandez, Neus Lozano, Kostas Kostarelos*, Thomas Kisby*
FULL ABSTRACT
Nature Communications, 2025, 16, 3412
Plasma-to-tumour tissue integrated proteomics using nano-omics for biomarker discovery in glioblastoma
Xinming Liu, Hanan Abmanhal-Masarweh, Olivia Iwanowytsch, Emmanuel Okwelogu, Kiana Arashvand, Konstantina Karabatsou, Pietro I D'Urso, Federico Roncaroli, Kostas Kostarelos, Thomas Kisby*, Marilena Hadjidemetriou*
FULL ABSTRACT
Nature Communications, 2025, 16, 2891
Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats
Nicola Ria, Ahmed Eladly, Eduard Masvidal, Xavi Illa, Anton Guimerà, Kate Hills, Ramon Garcia, Fikret Taygun Duvan, Samuel Flaherty, Michal Prokop, Rob. C Wykes*, Kostas Kostarelos*, Jose A. Garrido*
FULL ABSTRACT
Cell Reports Physical Science, 2025, 6, 1, 1102342
Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets
Maria Stylianou, Thomas Kisby*, Despoina Despotopoulou, Helen Parker, Alexandra Thawley, Kiana Arashvand, Neus Lozano, Andrew S. MacDonald, Kostas Kostarelos*
FULL ABSTRACT
ACS Nano 2025, 19, 11, 10630–10717
Interfacing with the brain: How nanotechnology can contribute
Abdullah A. A. Ahmed, Nuria Alegret, Bethany Almeida, Ramon Alvarez-Puebla, Anne M. Andrews, Laura Ballerini, Juan J. Barrios-Capuchino, Charline Becker, Robert H. Blick, Shahin Bonakdar, Indranath Chakraborty, Xiaodong Chen, Jinwoo Cheon, Gerwin Chilla, Andre Luiz Coelho Conceicao, James Delehanty, Martin Dulle, Alexander L. Efros, Matthias Epple, Mark Fedyk, Neus Feliu, Miao Feng, Rafael Fernandez-Chacon, Irene Fernandez-Cuesta, Niels Fertig, Stephan Forster, Jose A. Garrido, Michael George, Andreas H. Guse, Norbert Hampp, Jann Harberts, Jili Han, Hauke R. Heekeren, Ulrich G. Hofmann, Malte Holzapfel, Hessam Hosseinkazemi, Yalan Huang, Patrick Huber, Taeghwan Hyeon, Sven Ingebrandt, Marcello Ienca, Armin Iske, Yanan Kang, Gregor Kasieczka, Dae-Hyeong Kim, Kostas Kostarelos, Jae-Hyun Lee, Kai-Wei Lin, Sijin Liu, Xin Liu, Yang Liu, Christian Lohr, Volker Mailander, Laura Maffongelli, Saad Megahed, Alf Mews, Marina Mutas, Leroy Nack, Nako Nakatsuka, Thomas G. Oertner, Andreas Offenhauser, Martin Oheim, Ben Otange, Ferdinand Otto, Enrico Patrono, Bo Peng, Alessandra Picchiotti, Filippo Pierini, Monika Potter-Nerger, Maria Pozzi, Arnd Pralle, Maurizio Prato, Bing Qi, Pedro Ramos-Cabrer, Ute Resch Genger, Norbert Ritter, Marten Rittner, Sathi Roy, Francesca Santoro, Nicolas W. Schuck, Florian Schulz, Erkin Seker, Marvin Skiba, Martin Sosniok, Holger Stephan, Ruixia Wang, Ting Wang, K. David Wegner, Paul S. Weiss, Ming Xu, Chenxi Yang, Seyed Shahrooz Zargarian, Yuan Zeng, Yaofeng Zhou, Dingcheng Zhu, Robert Zierold, Wolfgang J. Parak*
FULL ABSTRACT
Nature Reviews Chemistry, 2025, 9, 173–184
Biological and environmental degradation of two-dimensional materials
Sandra Vranic^, Rajendra Kurapati^, Kostas Kostarelos*, Alberto Bianco*
FULL ABSTRACT
LAB SEMINARS
The Nanomedicine Lab regularly invites experts from diverse academic, research and industrial institutions, either as contributions to institutional seminar series or visiting the Lab and its facilities.
19/06/2025
Strategies to Promote Cancer Nanomedicine Clinical Performance
Prof. Dr. Twan Lammers
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14/02/2025
Nanoscale optics with plasmonic lattices
Prof. Teri W. Odom
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10/06/2024
Synthesis and application of 1D vdW heterostructures based on single-walled carbon nanotubes
Prof. Shigeo Maruyama
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13/07/2023
Boosting 2D materials with molecules: from high-performance multiresponsive electronics to pressure sensing for health monitoring
Prof. Paolo Samorì
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03/03/2023
Microfluidic manufacturing of nanoparticles: production considerations
Prof. Yvonne Perrie
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26/01/2023
Injury programmes shape glioblastoma
Prof. Simona Parrinello
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14/07/2022
Flexible electronics for neural interfaces
Prof. Jonathan Viventi
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21/04/2022
The Robotics Part of Micro and Nano Robotics
Prof. Bradley Nelson
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10/03/2022
Barcoded Nanoparticles for Precision Cancer Medicine: Effects of tumor type and patient sex on anticancer efficacy
Prof. Avi Schroeder
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27/01/2022
Micro/Nano engineering and drug delivery
Prof. Anja Boisen
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25/11/2021
Technology for bioelectronic medicine
Prof. George Malliaras
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14/10/2021
Translational research in organic neuroprosthetics
Prof. Diego Ghezzi
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13/02/2020
Directed growth and assembly of gold nanocrystals for bioapplications
Prof. Luis Liz-Marzán
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LAB NEWSVIEW ALL
30/06/2025
Talk on Graphene in Medicine at the Graphene2025 Conference
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26/06/2025
The World Economic Forum selects INBRAIN to join its Technology Pioneers
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19/06/2025
Twan Lammers visits Nanomedicine Lab
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10/06/2025
Nanomedicine at the EU IndTech conference in Kraków
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05/06/2025
Inspiring the next generation of scientists!
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03/06/2025
Despoina gives a talk at the Intracranial Glioma Workshop
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29/05/2025
Kostas speaks at the 20-year anniversary of the ETPN (NME25) meeting in Barcelona
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27/05/2025
José and Kostas receive the 2024 City of Barcelona Award in Science and Technology
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13/05/2025
SKIN2DTRONICS Kick-off meeting
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