The Nanoomics Technology Platform
We are developing nanoparticle-based enrichment platforms to facilitate in-depth analysis of the blood proteome and to harvest disease–specific molecular fingerprints.
LAB PUBLICATIONSVIEW ALL
bioRxiv, 2025, in press
Graphene micro-transistor arrays reveal perfusion-dependent electrophysiological and haemodynamic signatures of cortical spreading depolarizations in ischaemic stroke
S. Flaherty, A. Eladly, K. Hills, J. Merlini, E. Masvidal-Codina, E. Fernandez, X. Illa, E. Prats-Alfonso, E. Del Corro, J.A. Garrido, J. Meents, K. Kostarelos, S Allan, A. Guimerà-Brunet*, R.C. Wykes*
FULL ABSTRACT
Nature Reviews Clinical Oncology, 2025, 22
Targeting the glioblastoma resection margin with locoregional nanotechnologies
Thomas Kisby, Gerben R. Borst, David J. Coope, Kostas Kostarelos*
FULL ABSTRACT
Journal of Nanobiotechnology 23, 393 (2025)
Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells
Yingxian Chen, Vinicio Rosano, Neus Lozano, YuYoung Shin, Aleksandr Mironov, David Spiller, Cinzia Casiraghi, Kostas Kostarelos*, Sandra Vranic*
FULL ABSTRACT
bioRxiv, 2025, in press
An artefact-resilient wide bandwidth bidirectional graphene neural interface
Michał Prokop, Martín Esparza-Iaizzo, Eduard Masvidal-Codina, Xavi Illa, Neela K. Codadu, Daman Rathore, Nicola Ria, Kostas Kostarelos, Elena del Corro, Ramon Garcia-Cortadella, Rob C. Wykes, Anton Guimerà-Brunet*, Jose A. Garrido*
FULL ABSTRACT
bioRxiv, 2025, in press
Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing post-operative spatiotemporal blood-brain barrier disruption
Lorena F. Fernandes, Chariya Peeyatu, Ben R. Dickie, Yu Siong Ho, Lydia A. Thompson, Noelia Hernandez, Neus Lozano, Kostas Kostarelos*, Thomas Kisby*
FULL ABSTRACT
Nature Communications, 2025, 16, 3412
Plasma-to-tumour tissue integrated proteomics using nano-omics for biomarker discovery in glioblastoma
Xinming Liu, Hanan Abmanhal-Masarweh, Olivia Iwanowytsch, Emmanuel Okwelogu, Kiana Arashvand, Konstantina Karabatsou, Pietro I D'Urso, Federico Roncaroli, Kostas Kostarelos, Thomas Kisby*, Marilena Hadjidemetriou*
FULL ABSTRACT
Nature Communications, 2025, 16, 2891
Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats
Nicola Ria, Ahmed Eladly, Eduard Masvidal, Xavi Illa, Anton Guimerà, Kate Hills, Ramon Garcia, Fikret Taygun Duvan, Samuel Flaherty, Michal Prokop, Rob. C Wykes*, Kostas Kostarelos*, Jose A. Garrido*
FULL ABSTRACT
Cell Reports Physical Science, 2025, 6, 1, 1102342
Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets
Maria Stylianou, Thomas Kisby*, Despoina Despotopoulou, Helen Parker, Alexandra Thawley, Kiana Arashvand, Neus Lozano, Andrew S. MacDonald, Kostas Kostarelos*
FULL ABSTRACT
ACS Nano 2025, 19, 11, 10630–10717
Interfacing with the brain: How nanotechnology can contribute
Abdullah A. A. Ahmed, Nuria Alegret, Bethany Almeida, Ramon Alvarez-Puebla, Anne M. Andrews, Laura Ballerini, Juan J. Barrios-Capuchino, Charline Becker, Robert H. Blick, Shahin Bonakdar, Indranath Chakraborty, Xiaodong Chen, Jinwoo Cheon, Gerwin Chilla, Andre Luiz Coelho Conceicao, James Delehanty, Martin Dulle, Alexander L. Efros, Matthias Epple, Mark Fedyk, Neus Feliu, Miao Feng, Rafael Fernandez-Chacon, Irene Fernandez-Cuesta, Niels Fertig, Stephan Forster, Jose A. Garrido, Michael George, Andreas H. Guse, Norbert Hampp, Jann Harberts, Jili Han, Hauke R. Heekeren, Ulrich G. Hofmann, Malte Holzapfel, Hessam Hosseinkazemi, Yalan Huang, Patrick Huber, Taeghwan Hyeon, Sven Ingebrandt, Marcello Ienca, Armin Iske, Yanan Kang, Gregor Kasieczka, Dae-Hyeong Kim, Kostas Kostarelos, Jae-Hyun Lee, Kai-Wei Lin, Sijin Liu, Xin Liu, Yang Liu, Christian Lohr, Volker Mailander, Laura Maffongelli, Saad Megahed, Alf Mews, Marina Mutas, Leroy Nack, Nako Nakatsuka, Thomas G. Oertner, Andreas Offenhauser, Martin Oheim, Ben Otange, Ferdinand Otto, Enrico Patrono, Bo Peng, Alessandra Picchiotti, Filippo Pierini, Monika Potter-Nerger, Maria Pozzi, Arnd Pralle, Maurizio Prato, Bing Qi, Pedro Ramos-Cabrer, Ute Resch Genger, Norbert Ritter, Marten Rittner, Sathi Roy, Francesca Santoro, Nicolas W. Schuck, Florian Schulz, Erkin Seker, Marvin Skiba, Martin Sosniok, Holger Stephan, Ruixia Wang, Ting Wang, K. David Wegner, Paul S. Weiss, Ming Xu, Chenxi Yang, Seyed Shahrooz Zargarian, Yuan Zeng, Yaofeng Zhou, Dingcheng Zhu, Robert Zierold, Wolfgang J. Parak*
FULL ABSTRACT
Nature Reviews Chemistry, 2025, 9, 173–184
Biological and environmental degradation of two-dimensional materials
Sandra Vranic^, Rajendra Kurapati^, Kostas Kostarelos*, Alberto Bianco*
FULL ABSTRACT
