Articles | 2012

Journal of the American Chemical Society, 2012, 134: 13256−13258

Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

N.Lozano, W.T.Al-Jamal, A.Taruttis, N.Beziere, N.Burton, J.Van den Bossche, M.Mazza, E.Herzog, V.Ntziachristos*, K.Kostarelos*

The design of liposome−nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome− gold nanorod hybrid vesicular system that consists of lipidbilayer- associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

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