Articles | 2005

Journal of Nuclear Medicine, 2005, 46(1):89-97

Liposome-mediated radiotherapeutics within avascular tumor spheroids: comparative dosimetry study for various radionuclides, liposome systems and a targeting antibody

D. Emfietzoglou, K.K ostarelos, A. Papakostas, W-H. Yang, A. Ballangrud, H. Song, G. Sgouros

Absorbed dose profiles within tumor spheroids simulating avascular micrometastases have been calculated for a variety of liposome- and antibody-radionuclide combinations to assess the anticipated therapeutic efficacy based on the intratumoral distribution of the carrier systems within the spheroid model.

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