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Articles | 2013

Advanced Healthcare Materials, 2013, 2( 6) pp 806–811

Electroresponsive polymer-carbon nanotube hydrogel hybrids for pulsatile drug delivery in vivo

A.Servant, L.Methven, R.P.Williams, K.Kostarelos*

Drug release triggered by an external non-invasive stimulus is of great interest for the development of new drug delivery systems. The preparation of an electroresponsive multiwalled carbon nanotube/poly(methylacrylic acid) (MWNT/PMAA)-based hybrid material is reported. The hydrogel hybrids achieve a controlled drug release upon the ON/OFF application of an electric field, giving rise to in vitro and in vivo pulsatile release profiles.

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