Archives in Toxicology, 2012, 86(7): 1009-1020
Application of carbon nanotubes in neurology: clinical perspectives and toxicological risks
Nanomedicine is an emerging field that proposes the application of precisely engineered nanomaterials for the prevention, diagnosis and therapy of certain diseases, including neurological pathologies. Carbon nanotubes (CNT) are a new class of nanomaterials, which have been shown to be promising in different areas of nanomedicine. In this review, the application of CNT interfacing with the neuronal tissue and the central nervous system (CNS) environment along with will be described, and representative examples of neuroprosthetic devices, such as neuronal implants and electrodes will be provided. Furthermore, the possible application of CNT-based materials as regenerative matrices of neuronal tissue and as delivery systems for the therapy of CNS will be presented.